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To the Best of Our Knowledge

To The Best of Our Knowledge is a captivating radio show produced by Wisconsin Public Radio that explores a vast range of topics through interviews, storytelling, and thought-provoking discussions. From science and philosophy to arts and culture, the program delves deep into the complexities of the human experience, uncovering fascinating insights and engaging listeners with diverse perspectives and meaningful conversations.

  • Can neuroscience explain what happens to the brain on psychedelics? And even if we map the brain while it’s tripping, does that tell us why these experiences can be so transformative? We’ll talk with some of the pioneers in psychedelic research — from Amanda Feilding’s boundary-busting work to Robin Carhart-Harris’ theory of the "entropic brain." Also, renowned neuroscientist Christof Koch goes down the rabbit hole on 5-MeO-DMT, also known as toad venom. Original Air Date: July 15, 2023 Interviews In This Hour: Exploring consciousness on toad venom — The godmother of the European psychedelic revival — How therapeutic psilocybin could help heal long-buried trauma — Magic mushrooms and the 'entropic brain' Guests: Christof Koch, Amanda Feilding, David Nutt, Robin Carhart-Harris Never want to miss an episode? Subscribe to the podcast. Want to hear more from us, including extended interviews and favorites from the archive? Subscribe to our newsletter.
  • From our narrow vantage point on Earth, how can we see what's out there, beyond our skies? We look to how scientists and scholars have studied eclipses, dark matter, deep-space transmissions from intelligent life and more, all in the hopes of painting a clearer picture of a vast and invisible universe. Original Air Date: August 19, 2017 Interviews In This Hour: How Eclipse Chasing Inspires Generations of Scientists — How Do We Investigate The Invisible Parts of the Universe? — Search For Life In All The Wrong Places — What Can You Hear In Space? — The Universe Is Under No Obligation To Make Sense To Us Guests: David Baron, Priya Natarajan, Seth Shostak, Don Gurnett, Neil deGrasse Tyson Further Reading: NASA: 2024 Eclipse Explorer Never want to miss an episode? Subscribe to the podcast. Want to hear more from us, including extended interviews and favorites from the archive? Subscribe to our newsletter.
  • AI can do amazing things – write your term papers, sequence your genes, maybe replace your therapist. But even super-intelligence has limits. So, does AI really have a mind — or a soul? We'll explore the frontiers of artificial intelligence — from robots painting masterpieces to software engineers trying to create god-like machines. Original Air Date: March 30, 2024 Interviews In This Hour: Stop worrying about deepfakes — Does AI have a soul? — Can robots paint a masterpiece? Guests: Walter Scheirer, Meghan O’Gieblyn, Sougwen 愫君 Chung Never want to miss an episode? Subscribe to the podcast. Want to hear more from us, including extended interviews and favorites from the archive? Subscribe to our newsletter.
  • We all feel better after a good cry. In fact, humans are the only animals who cry emotional tears. But what about people who don't cry? And have you ever wondered why a sad song or movie makes you cry? Original Air Date: August 05, 2023 Interviews In This Hour: Hip-hop artist Dxtr Spits on teaching men to cry — The evolution and neuroscience of tears — What happens when an actor cries Guests: Dxtr Spits, Michael Trimble, Jen Plants Never want to miss an episode? Subscribe to the podcast. Want to hear more from us, including extended interviews and favorites from the archive? Subscribe to our newsletter.
  • Pop music is a gazillion-dollar industry that churns out hits and creates celebrities. It seems like the definition of ephemeral – today’s chart topper is gone tomorrow. But pop music is a powerful vehicle for bringing people together, and fans - from K-pop to the #FreeBritney movement — have something to teach us about community and hope. Original Air Date: March 26, 2022 Interviews In This Hour: When we're disconnected, can we reconnect through K-pop? — From pop to punk: Shaping our musical identities — How a fan movement freed a pop star from her gilded cage Guests: Regina Kim, Kyla Nicole, Kelefa Sanneh, Samantha Stark Never want to miss an episode? Subscribe to the podcast. Want to hear more from us, including extended interviews and favorites from the archive? Subscribe to our newsletter.
  • In 2020, Donald Trump won 84 percent of the white evangelical vote.). Lately, he’s been leaning even more deeply into the rhetoric of Christian nationalists. Who are they, and what’s their role in the evangelical church? We talk with some Southern Baptists today, whose views may surprise you. Original Air Date: March 09, 2024 Interviews In This Hour: The 'simmering violence' of Donald Trump and Christian nationalism — Examining the Role of Southern Baptist Women — Why One Black Pastor Left the Southern Baptists Guests: Jeff Sharlet, Beth Allison Barr, John Onwuchekwa Never want to miss an episode? Subscribe to the podcast. Want to hear more from us, including extended interviews and favorites from the archive? Subscribe to our newsletter.
  • Colonization in Africa was much more than a land grab. It was a project to replace — and even erase — local cultures. To label them inferior. Music, arts, literature and of course language. In other words, it permeated everything. So how do you undo that? How do you unlearn what you’ve been forced to learn? In this hour, produced in partnership with the Consortium of Humanities Centers and Institutes (CHCI) and Africa is a Country — we learn what it means to decolonize the mind. Original Air Date: March 20, 2021 Interviews In This Hour: Reckon with the Past To Decolonize the Future — Reclaiming the Hidden History of Blackness — Never Write In The Language of the Colonizer Guests: Adom Getachew, Simon Gikandi, Ngugi wa Thiong’o Never want to miss an episode? Subscribe to the podcast. Want to hear more from us, including extended interviews and favorites from the archive? Subscribe to our newsletter.
  • What’s the last dream you remember having? Some of us dream every night. But we’re in too much of a hurry to remember our dreams or think about them the next day. Others of us are dream-deprived. What if we embrace our dreams — and our night selves — as a way to understand ourselves better, to connect to each other, even to lead a better life? Original Air Date: February 24, 2024 Interviews In This Hour: Why dream life matters — The lives we live inside our dreams — A dreaming mind, illustrated — Embracing your night self Guests: Rubin Naiman, Kelly Bulkeley, Roz Chast, Annabel Abbs-Streets Never want to miss an episode? Subscribe to the podcast. Want to hear more from us, including extended interviews and favorites from the archive? Subscribe to our newsletter.
  • In the first episode of "Luminous," our series about the philosophy and the future of psychedelics, how can psilocybin ease our fears about dying? And how can psychedelics change the way we approach the end of life? Original Air Date: April 08, 2023 Interviews In This Hour: How a pioneering psychedelic researcher 'leaned in' to his terminal cancer diagnosis — Dying without fear: How psychedelics can ease the anxiety of terminal illness — The terror and the ecstasy of psychedelics Guests: Roland Griffiths, Lou Lukas, Anthony Bossis Editorial note: Roland Griffiths passed away on Oct. 16, 2023. The conversation with him in this episode took place in January 2023. Never want to miss an episode? Subscribe to the podcast. Want to hear more from us, including extended interviews and favorites from the archive? Subscribe to our newsletter.
  • The bond we share with dogs runs deep. The satisfaction of gentle head scratches or a round of playing fetch is simple and pure, but in other ways, the connection we have is truly unknowable. How do dogs make our lives better? How do they think? And how do we give them the lives they deserve? Original Air Date: February 05, 2022 Interviews In This Hour: Adventure, goofiness and trail snacks: Stories from the dog musher's journal — Getting inside the mind of a dog — Nothing makes losing a dog easy. But a bridge dog can help. — Joy and peace, high up on Dog Mountain Guests: Blair Braverman, Quince Mountain, Donna Haraway, Sarah Miller Further Reading: Pet Loss Resource Center: Resources for animal loss and grief Never want to miss an episode? Subscribe to the podcast. Want to hear more from us, including extended interviews and favorites from the archive? Subscribe to our newsletter.