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Vaccination isn't a perfect defense against flu. But vaccines remain the most reliable way to reduce the risk from an illness that causes thousands of deaths in the U.S. during a typical flu season.

The last time Garth Brooks did six shows in Jacksonville, Veterans Memorial Arena was a Coliseum, people still bought their music in CD form and Mark…

The American League Championship Series begins tonight. Writer Kate Tuttle says Roger Angell's 1988 collection of essays, Season Ticket, is the perfect accompaniment to the postseason.

The antibiotic-resistant bacteria C. difficile can be deadly. Fecal transplants often can cure infections but have a major ick factor. Capsules of fecal matter deliver the cure more politely.

Neil Young loves his cars so much he wrote a second memoir, Special Deluxe, devoted to them. He speaks with NPR's Ari Shapiro about music, the environment and, of course, automobiles.

Every answer is the name of a popular prime-time TV series from this century, on either broadcast or cable. Identify the shows from their anagrams.

Water is a crucial resource to those living along the Tigris and Euphrates rivers. NPR's Ari Shapiro talks to researcher Matthew Machowski about how ISIS is using that natural resource as a weapon.

This month, the National Portrait Gallery presented its largest portrait yet, a 6-acre face rendered in sand and soil on the National Mall.

Shoppers are heading into the heavy-spending season with no new credit safeguards in place. Experts say it'll be at least another year before the U.S. system moves beyond technology from the 1970s.

When blood flows over an artificial surface, whether it's an implanted pacemaker or tubing for a dialysis machine, there's an increased risk that a dangerous clot will form.